Dr. Paul Perella, DMD


A study by the Department of Anesthesiology at Duke University Medical Center in Durham, North Carolina believes that gender appears to be an important variable in recovery from general anesthesia. These findings may explain the increased reported incidence of awareness in women and support the need to include gender as a variable in pharmacokinetic and pharmacodynamic studies of anesthetic drugs. That is, the study of what a drug does to a body and what a body does to a drug.

Even though gender could make a difference in the conclusion of studies using nitrous oxide, it appears that gender doesn't makemuch of a difference. Only one study, using only men, which took place at the Service de Physiologie-Explorations Fonctionnelles, Hôpital Henri Mondo, Creteil, France found that nitrous oxide can induce central and obstructive sleep apnea.

The Department of Anesthesia & Critical Care at the University of Chicago states that there does not appear to be differences in how healthy male and female volunteers report feeling from the effects of 30% N2O.



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